hypersensitivity to the drug or any other components contained in the capsule;
chronic malabsorption syndrome;
Use in pregnancy and breastfeeding:
Product categories in.
In reproductive toxicity studies on animals teratogenic and embryotoxic effects of the drug were observed. In the absence of teratogenic effects in animals expect such an effect in humans should not be. However, due to the lack of clinical data Xenical should not assign pregnant women.
xenical excretion in breast milk has not been studied, so it should not be taken during lactation. Side effects:
To describe the frequency of adverse reactions, the following categories are used: very common 1/10), common 1/100, 1/10 uncommon 1/1000, 1/100 rare 1/10000, 1/1000 and very rare (1/10000 including individual cases. Category actions on the fetus by the FDA is X.
It is not known whether orlistat secretiruetsa in breast milk, it should not be applied in nursing women. Side effects:
Controlled clinical trials
According to the seven double-blind, placebo-controlled clinical trials in patients taking orlistat on 120 mg 3 times a day on a diet during the first and second year of monitoring the most frequently 5%) frequency and at least 2 times more frequently than in the placebo group (on a diet), there were side effects from the blood, which reflect the action of the drug (see table 3).
The most common side effects observed in clinical trials xenical These and other commonly observed adverse reactions were mainly moderate and transient, their frequency declined in the second year of treatment. In General, the first episode of side effects was observed within 3 months from the beginning of therapy. The length of 50% of all gastrointestinal side effects associated with treatment orlistatom, less than 1 hour, in most cases, no more than 4 weeks. However, the side effects from the blood in some patients may develop within 6 months and more therapy.
In controlled clinical trials, discontinue treatment due to side effects were forced to 8.8% of patients taking orlistat, compared to 5% in the placebo group. xenical group most frequently interrupted treatment due to side effects from the stomach.
When treating Ksenikalom often experience the following adverse effects from the stomach: soft stools, pain or discomfort in the rectum, faecal incontinence, bloating, loss of teeth, damage to the gums.
There were also very often headaches, upper respiratory tract infection, flu; often, an infection of the lower respiratory tract, urinary tract infections, dysmenorrhea, anxiety, weakness.
Described rare cases of allergic reactions, the main clinical symptoms which have been itching, rash, urticaria, angioneuroticeski swelling, bronhospazm, and anaphylaxis.
Describes very rare cases and Bullous rashes, raising transaminaz and ALP, as well as individual, perhaps serious cases of hepatitis (causal link with taking Xenical or pathophysiological mechanisms are not installed).
While appointing Xenical and anticoagulants reduce cases of prothrombin, increasing the MNO.
xenical no prescription
Cases of rectal bleeding, diverticulitis, pancreatitis and cholelithiasis (frequency of occurrence is unknown).
Symptoms: in cases of overdose have been reported either about the absence of adverse events or adverse effects did not differ from those observed in the employment drug in therapeutic doses.
Treatment: in the event of overdose recommended Xenical expressed observe patient for 12:00 am
According to studies in humans and animals, any systemic effects that can be associated with lipazoingibiruusimi properties xenical, must be quickly reversible. Dosage and administration:
Inside, adults to 1 caps. (120 mg) with each main meal (at the time, or not later than 1 hour after eating). If you miss a meal or food does not contain fat, then taking the drug also can be ignored.
Increase dose xenical over recommended (120 mg 3 times daily) does not lead to the strengthening of its therapeutic effect.
Dose adjustment in elderly patients is not required.